Staff at the site reported a fire had broken out at 6am and the fire brigade arrived soon after. The area was evacuated and nobody is believed to be hurt.
The M6 was closed northbound and southbound between junctions 29 to 32 but reopened shortly after 11am.
Approximately 62,000 litres of flammable waste liquid was burning and the fire was still being dampened down in the early afternoon. Firefighters focused their attention on protecting a large single storey building said to be containing a large number of cylinders.
Veolia said it will investigate the incident at its centre on the Red Scar Industrial Estate, Ribbleton as soon as it is safe to do so.